Background: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.Product datasheet: Overview Product Description sMtCK Polyclonal Antibody, 100µg, (ATB-T4347) Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the Internal region of human sMtCK. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year Clonality Polyclonal References: Separate nuclear genes encode sarcomere-specific and ubiquitous human mitochondrial creatine kinase isoenzymes. Haas R.C., Strauss A.W.J. Biol. Chem. 265:6921-6927(1990) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Heart. Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201). Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). The MGC Project TeamGenome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain. Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase. Haas R.C., Korenfeld C., Zhang Z., Perryman B., Roman D., Strauss A.W.J. Biol. Chem. 264:2890-2897(1989) [PubMed] [Europe PMC] Cited for: PROTEIN SEQUENCE OF 40-65. Crystal structure of human sarcomeric mitochondrial creatine kinase. Structural genomics consortium (SGC)Submitted (APR-2006) to the PDB data bankCited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 27-416 IN COMPLEX WITH ADP.
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