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SSX Polyclonal Antibody, 100μg, (ATB-T15185)

SSX Polyclonal Antibody, 100μg, (ATB-T15185)

Store / Antibodies and Immunodetection Reagents / Primary Antibodies
$199.00
In stock
Product Details

Background: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013]Product datasheet: Overview Product Description SSX Polyclonal Antibody, 100μg, (ATB-T15185) Image Species Reactivities Human Immunogen Synthesized peptide derived from the C-terminal region of human SSX. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: A poorly differentiated synovial sarcoma arising from the pulmonary valve. Yin L, et al. Cardiovasc Pathol, 2013 Nov-Dec. PMID 23701986 Testicular synovial sarcoma: a case report. Nesrine M, et al. Cancer Biol Med, 2012 Dec. PMID 23691490 Free PMC Article Primary gastric synovial sarcoma. Wang CC, et al. J Formos Med Assoc, 2012 Sep. PMID 23021509 A case of primary synovial sarcoma of the thorax with a variant SYT-SSX1 fusion transcript. Morikawa H, et al. Ann Thorac Surg, 2009 Jul. PMID 19559255 Localization of X chromosome short arm markers relative to synovial sarcoma- and renal adenocarcinoma-associated translocation breakpoints. Sinke RJ, et al. Hum Genet, 1993 Oct 1. PMID 8406438

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SSX Polyclonal Antibody, 100μg, (ATB-T15185)
Store / Antibodies and Immunodetection Reagents / Primary Antibodies
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