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NanoSurface ANFS 6 Well Cell Culture Plate, ANFS nano surface, sterile, 1, 5 or 10 plates/pack

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NanoSurface ANFS 6 Well Cell Culture Plate, ANFS nano surface, sterile, 1, 5 or 10 plates/pack Features. Nanopattern with 800nm 1:1 Ridge to Groove Spacing Modulus range close to that of overall muscle tissue (6.69 MPa) Bio-compatible PUA Dish size: 35 mm Hole size: 20Ø Plate size: 6, 24 or 96 well plate Gamma sterilized Functional Test. Sterility Passed Cytotoxicity Passed Non-Pyrogenic Passed RNase/DNase Free Background There are many examples of how nanotopographic structures throughout tissues and organs within multi-cellular organisms influence cellular behavior. With lithographic manufacturing technology, it nowis possible to precisely fabricatebiomimeticnanotopographic structures within a cell culture device that producea more 'natural' cellular behavior within acell population. Numerous in vitro studiesutilizingfabricated nanotopograhic featuresdemonstratehowbiomimetic nanostructuresimpact cellular behaviors (e.g. cell morphology and cell differentiation) and physiology. The following figure shows howcellsexhibit different morphologies depending on whether or not the culture surfaceis flat or grooved. ANFS (Anisotropically NanoFabricated Substratum) Technology Nanostructure with 800 nm wide, 600 nm ridges/grooves is created with nanofabrication. ANFS Cell/Tissue Culture Dish and Plates Cell and Tissue Culture with ANFS Surface Human iPSC derived cardiomyocytes (left panel) andEndothelial cells (EA.hy926 human ECs) (Right Panel)cultures grown on either a flat or ANFS surface. Easy to Use ANFS Cell Culture Protocol Documents ANFS Technology Brochure ANFS Cell Culture Products Brochure ANFS dish and 6 Well Plate Product Sheet Published Cell Adhesion Data on ANFS Surface Nanosurface Protocol Publication References Cell Type Publication 1 Cardiomyocytes Kim et al., PNAS. 2010, 107(2), 565-570 2 Human iPSC derived cardiomyocytes Macadangdang et al, Cellular and Molecular Bioengineering. 2015, 8(3), 320-332 3 Smooth muscle cells Nemeth et al. Tissue Engineering: Part A. 20(21 and 22), 2817-2829 4 Endothelial cells (EA.hy926 human ECs) Jeon et al. ACS Applied Materials and Interfaces. 2015, 4525-4531 5 NIH 3T3 fibroblast cells Kim et al. Biomaterials, 2009, 30(29), 54335444 6 Dental pulp stem cells Nemeth et al. Tissue Engineering: Part A. 20(21 and 22), 2817-2829 7 Human mesenchymal stem cells J. Kim et al. Scientific Reports 3, Article number: 3552 (2013) 8 Pre-adipocytes (3T3-L1) M.S. Kim et al Nanotechnology Journal, Volume 22, Issue Number 49

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NanoSurface ANFS 6 Well Cell Culture Plate, ANFS nano surface, sterile, 1, 5 or 10 plates/pack
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