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JIP-2 Polyclonal Antibody, 100μg, (ATB-T2435)

$199.00
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Product Details

Background: The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. [provided by RefSeq, Feb 2014]Product datasheet: Overview Product Description JIP-2 Polyclonal Antibody, 100μg, (ATB-T2435) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from the C-terminal region of human JIP-2. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Evaluation of PKM2 and MAPK8IP2 Polymorphism in Ameloblastic Carcinoma: A Retrospective Quantitative Study. Khodayari A, et al. Int J Mol Cell Med, 2012 Fall. PMID 24551779 Free PMC Article Cerebellar and posterior fossa malformations in patients with autism-associated chromosome 22q13 terminal deletion. Aldinger KA, et al. Am J Med Genet A, 2013 Jan. PMID 23225497 Free PMC Article Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2. Giza J, et al. J Neurosci, 2010 Nov 3. PMID 21048139 Free PMC Article Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism. Taru H, et al. J Biol Chem, 2002 Jul 26. PMID 12023290 Fibroblast growth factor homologous factors are intracellular signaling proteins. Schoorlemmer J, et al. Curr Biol, 2001 May 15. PMID 11378392 Free PMC Article

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JIP-2 Polyclonal Antibody, 100μg, (ATB-T2435)
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