Background: The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description IL-20 Polyclonal Antibody, 100μg, (ATB-T2324) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the Internal region of human IL-20. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: The correlation between IL-20 and the Th2 immune response in human asthma. Wu J, et al. Asian Pac J Allergy Immunol, 2014 Dec. PMID 25543042 Interleukin 20 protein locates to distinct mononuclear cells in psoriatic skin. Bech R, et al. Exp Dermatol, 2014 May. PMID 24628979 Decreased interleukin-20 expression in scleroderma skin contributes to cutaneous fibrosis. Kudo H, et al. Arthritis Rheumatol, 2014 Jun. PMID 24470401 Decreased interleukin-20 level in patients with systemic sclerosis: are they related with angiogenesis? Aydoğdu E, et al. Clin Rheumatol, 2013 Nov. PMID 23812620 Genetic polymorphisms of interleukin 20 (IL-20) in patients with ulcerative colitis. Yamamoto-Furusho JK, et al. Immunol Lett, 2013 Jan. PMID 23183096
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