Background: This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description BRD3 Polyclonal Antibody, 100μg, (ATB-T0522) Image Species Reactivities Human,Mouse Immunogen Synthesized peptide derived from the C-terminal region of human BRD3. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Identification of a BET family bromodomain/casein kinase II/TAF-containing complex as a regulator of mitotic condensin function. Kim HS, et al. Cell Rep, 2014 Mar 13. PMID 24565511 Free PMC Article Detection of the genes induced in activated lymphocytes by modified differential display. Kaneko H, et al. J Investig Allergol Clin Immunol, 2002. PMID 12371535 Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3. Gamsjaeger R, et al. Mol Cell Biol, 2011 Jul. PMID 21555453 Free PMC Article The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription. LeRoy G, et al. Mol Cell, 2008 Apr 11. PMID 18406326 Free PMC Article Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene. Thorpe KL, et al. Gene, 1997 Oct 24. PMID 9373153
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