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Anti RET(C634Y) Mouse Monoclonal Antibody, 100 ul (26146)

Anti RET(C634Y) Mouse Monoclonal Antibody, 100 ul (26146)

Store / Antibodies and Immunodetection Reagents / Primary Antibodies / Antibodies for Biomarkers
$495.00
In stock
Product Details

RET(C634Y) [26146] [100ul] Catalog Number: 26146 Gene Symbol: RET, PTC, CDHF12, CAHF16, HSCR1, MEN2A, MEN2B Description: Anti RET(C634Y) Mouse Monoclonal Antibody Background: RET protein is encoded by the RET proto- oncogene. It is a receptor tyrosine kinase. RET loss of function mutations are associated with the development of Hirschsprungs disease, while gain of function mutations are associated with development of various types of human cancer, including medullary thyroid carcinoma, multiple endocrine neoplasias type 2A and 2B, pheochromocytoma and parathyroid hyperplasia. Immunogen: A synthetic peptide from the internal region of RET which includes the mutation of C634Y, human origin. Applications: ELISA, WB, IHC Recommended Dilutions: ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100 Concentration: 0.5 mg/ml Host: Mouse Format: Liquid Clonality: Monoclonal Isotype: Purity: Purified from ascites Storage buffer: Preservative:no Constituents:PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol Species Reactivity: Recognizes C634Y mutant, but not wild-type RET of vertebrates. Storage Conditions: Store at -20C. Avoid freeze / thaw cycles Download Datasheet: Western blot: Western blot analysis of recombinant RET(C634Y) and wildtype proteins. Purified His-tagged RET(C634Y) protein (lane1) and corresponding wild-type protein (lane2) were blotted with Anti RET(C634Y) monoclonal antibody (Cat. #26146). Immunoprecipitation/Western blot: Immunofluorescence of cells expressing RET proteins with Anti RET(C634Y) antibody. HEK293T cells were transfected with pCDNA3-GFP-RET (WT) plasmid (left column) or pCDNA3-GFP-RET(C634Y) plasmid (right column), then fixed and stained with Anti RET(C634Y) monoclonal antibody (Cat. #26146).

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Anti RET(C634Y) Mouse Monoclonal Antibody, 100 ul (26146)
Store / Antibodies and Immunodetection Reagents / Primary Antibodies / Antibodies for Biomarkers
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