Anti-Huamn sphingosine 1-phosphate receptor 1 (S1PR1) Mouse Monoclonal Antibody (DBOA10006), 100 ugy Any application comments (selling point?) S1PR1 Antibody images Western Blotting and IHC image Background Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene. S1PR1 is a G-protein-coupled receptor which binds the bioactive signaling molecule sphingosine 1-phosphate (S1P). S1PR1 belongs to a sphingosine-1-phosphate receptor subfamily comprising five members (S1PR1-5).[1] S1PR1 was originally identified as an abundant transcript in endothelial cells[2] and it has an important role in regulating endothelial cell cytoskeletal structure, migration, capillary-like network formation and vascular maturation.[3][4] In addition, S1PR1 signaling is important in the regulation of lymphocyte maturation, migration and trafficking.[5][6] Product datasheet: Overview Product Name Anti-Huamn sphingosine 1-phosphate receptor 1 (S1PR1) Mouse Monoclonal Antibody (DBOA10006), 100 ug Description Anti-Huamn sphingosine 1-phosphate receptor 1 (S1PR1) Mouse Monoclonal Antibody (DBOA10006), 100 ug, can be used in studying S1PR1 protein expression in cultured cells or tissue samples. Tested Applications WB, IHC Species Reactivities Reacts with: c-myc tag Immunogen c-myc tag peptide Positive Control N/A Properties Form Freeze dried solid Storage Instructions Store at +4C long term. After reconstitution, Store at +4C short term (1-2 weeks). Aliquot and store at -20C long term. Avoid repeated freeze / thaw cycles. Storage Buffer When reconstituted with 100 deionized water, PBS with no preservatives. Constituent PBS Purity Purified by protein A Clonality Monoclonal Clone Name P1S Isotype IgG Applications The application notes include recommended starting dilutions; optimal dilutions or concentrations should be determined by the end user. WB 1/500 - 1/2000. IHC 1/200 - 1/1000
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