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Anti EGFR(S768I) Mouse Monoclonal Antibody, 100 ul (26483)
EGFR (S768I) 26483 [100ul] Catalog Number: 26483 Gene Symbol: EGFR/HER1/ERBB1 Description: AntiEGFR(S768I)Mouse Monoclonal Antibody Background: EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. Defects in EGFR are associated with lung cancer (LNCR). Immunogen: A synthetic peptide from the internal region of EGFR which includes the mutation of S768I, human origin. Applications: ELISA, WB, IF, IHC Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:1000-1:5000 IHC: 1:50-1:200 Concentration: 1 mg/ml Host: Mouse Format: Liquid Clonality: Monoclonal Isotype: Purity: Purified from ascites Storage buffer: Preservative:no Constituents:PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol Species Reactivity: Recognizes EGFR (S768I), but not wild type EGFR from vertebrates. Storage Conditions: Store at -20C. Avoid freeze / thaw cycles Download Datasheet: Western blot: Western blot analysis of recombinant EGFR (S768I) and wildtype proteins. Purified His-tagged EGFR (S768I) protein (lane 1) and corresponding wild type protein (amino acids 702-987, lane 2) were blotted with anti EGFR(S768I) mouse monoclonal antibody (Cat. #26483). Immunofluorescence: Immunofluorescence of cells expressing EGFR proteins with anti EGFR(S768I) antibody. HEK293T cells were transfected with pCDNA3-GFP-EGFR (WT) plasmid (left column) or pCDNA3-GFP EGFR(S768I) plasmid (right column), then fixed and stained with anti- EGFR (S768I) monoclonal antibody (Cat. #26483).
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At IntelixBio, our dedication to advancing healthcare is exemplified through our unparalleled range of medical lab equipment. Each product is meticulously crafted to meet the exacting standards of modern laboratory environments, facilitating seamless integration and operation. Our commitment to quality permeates every aspect of our offerings, ensuring that laboratories can consistently rely on our medical lab equipment to deliver precise and dependable results. With a comprehensive selection that spans from basic laboratory essentials to sophisticated diagnostic instruments, IntelixBio remains the foremost choice for institutions seeking excellence in medical equipment solutions. Trust IntelixBio to elevate your laboratory capabilities with our innovative medical lab equipment, empowering you to drive progress in healthcare delivery.
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