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AR-β2 Polyclonal Antibody, 100μg, (ATB-T5048)

AR-β2 Polyclonal Antibody, 100μg, (ATB-T5048)

Store / Antibodies and Immunodetection Reagents / Primary Antibodies
$199.00
In stock
Product Details

Background: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]Product datasheet: Overview Product Description AR-β2 Polyclonal Antibody, 100μg, (ATB-T5048) Image Species Reactivities Human,Mouse,Rat Immunogen Synthesized peptide derived from human AR-β2 around the non-phosphorylation site of S355/S356. Properties Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions-20°C/1 year References: Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis. Tsvetanova NG, et al. Nat Chem Biol, 2014 Dec. PMID 25362359 Interaction of the ADRB2 gene polymorphism with childhood trauma in predicting adult symptoms of posttraumatic stress disorder. Liberzon I, et al. JAMA Psychiatry, 2014 Oct. PMID 25162199 Relationship between polymorphisms in beta -2 adrenergic receptor gene and ischemic stroke in North Indian Population: a hospital based case control study. Kumar A, et al. BMC Res Notes, 2014 Jun 25. PMID 24966013 Free PMC Article Association of genetic polymorphisms at beta-adrenergic receptor with risk of intracerebral hemorrhagic stroke in North Indian population: a case control study. Kumar A, et al. Neurol India, 2014 Mar-Apr. PMID 24823730 Association of beta 2 adrenoceptor gene polymorphisms in Malaysian hypertensive subjects. Komara M, et al. Genet Mol Res, 2014 Apr 16. PMID 24782128

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AR-β2 Polyclonal Antibody, 100μg, (ATB-T5048)
Store / Antibodies and Immunodetection Reagents / Primary Antibodies
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